2-甲氧基-4-氧代-3-氧杂双环3．1．0己烷-6,6-二甲酸二乙酯的合成及结构表征

摘要

5-甲氧基-2(5H)-呋喃酮与溴代丙二酸二乙酯通过Michael加成、分子内亲核取代反应得到了环丙烷/丁内酯衍生物2-甲氧基-4-氧代-3-氧杂双环[3．1．0]己烷-6,6-二甲酸二乙酯,其结构通过1H NMR、13C NMR、X-射线单晶衍射进行了确认。%A cyclopropane/butyrolactone derivative 2-methoxy-4-oxo-3-oxa-bicyclo[3. 1. 0] hexane-6,6-dicarboxylate was synthe-sized through Michael addition,internal nucleophilic substitution reaction of 5-methoxy-2(5H)-furanone and bromomalonic acid di-ethyl ester. The structure of the title compound was confirmed through 1 H NMR、13 C NMR and X-ray single crystal diffraction.