Friedel-Crafts酰基化催化剂的研究进展

摘要

Friedel-Crafts酰基化反应在有机合成研究与现代工业生产中有着非常重要的作用,其催化剂主要有Lewis酸、超强酸/盐、离子液体、沸石类以及负载型催化剂。本文分别介绍了上述五类催化剂在F-C酰基化反应中的发展沿革与目前应用情况,分析评价了各类催化剂在该反应中的优缺点,并重点综述了沸石类催化剂和负载型催化剂的研究现状。最后从绿色化学、可持续发展的角度出发,指出沸石类和负载型两类催化剂具有较好的综合催化性能和工业化应用前景,值得进一步研究。%Friedel-Crafts acylation is a very important category of organic synthesis reactions in both academic and industrial fields,and the mostly used catalysts are Lewis acids,super acids and their metal salts,ionic liquids,zeolites and supported catalysts.This paper introduces the development history,current application,and advantages or disadvantages of the aforementioned catalysts,and especially focuses on zeolites and supported catalysts.Zeolites and supported catalysts are worthy of further study,since they have better overall properties and industrial catalysis prospects from the view of green chemistry and sustainable development.