微波辐射下有机锡催化合成对羟基苯甲酸甲酯

摘要

The reaction of dibutyltin oxide with 5-sulfosalicylicacid gave a new dibutyltin(IV) sulfonate which can be used as the catalysts for the synthesis of methylparaben under microwave irradiation. The effect of the synthetic conditions on the esterification were investigated. The advantages of the present procedure are high yields and short reaction time, the yield of methylparaben reached 93%.%本文以磺基水杨酸和二丁基氧化锡为原料合成了二丁基锡(IV)磺基水杨酸酯,并以此为催化剂,在微波辐射下合成了对羟基苯甲酸甲酯.文中探讨了微波功率、催化剂用量、反应时间、温度及醇酸摩尔比对酯合成收率的影响.实验结果表明,有机锡化合物在微波辐射下对酯化反应有良好的催化活性,对羟基苯甲酸甲酯的收率可达到93％.