水溶性8-羧酰胺基喹啉衍生物Zn2+荧光分子探针的研究

摘要

本文利用喹啉5位硝基取代的8-羧酰胺基喹啉衍生物设计、合成了一类荧光分子探针AQZ5NO,并研究了水溶液中探针分子对金属离子的识别性能.结果表明,在中性缓冲溶液中,AQZ5NO可以选择性荧光增强识别Zn2+.络合Zn2+后,AQZ5NO溶液的荧光量子产率增强约为11倍.AQZ5NO与Zn2+形成1:1型络合物,其表观结合常数为6.7×105M-1.%In this text, the 8 -carboxamidoquinoline -based fluorescence sensor AQZ5NO was synthesized through the introduction of the nitro group at position 5 of the quinoline ring. And the recognition performance for metal ions had been studied in neutral buffer solution. The results showed that AQZ5NO could exhibit fluorescent enhancement signals for Zn2+ with high selectivity. After binding Zn2+, about an 11 -fold increase of AQZ5N0 in fluorescence quantum yield was observed. There is the formation of a complex with 1:1 stoichiometry of AQZ5N0 and Zn2+, and its association constant is 6.7×l05M-1.