Trained through generations

摘要

The first scientists to coin the term“trained immunity”were Mihai G.Netea,Jessica Quintin,and Jos W.M.van der Meer in a‘Perspective’article in 2011[2].With the publication of vast amounts of experimental data and follow-up reviews,the concept that the innate immune system can develop a memory function in parallel to the well-recognized adaptive memory,mediated by B and T lymphocytes,is largely accepted.