A COMPARISON OF THE SENSITIVITY OF FOUR CELL STRAINS COMMONLY USED IN IN VITRO CLASTOGENICITY TESTS.

摘要

Several chemicals have been identified whichgive discordant results in clastogenicitytests in vitro using CH0 or CHL cells (Sofuniet al 1989).This observation has causedconcern and raised the question whether thesediscrepancies are attributable to qualitativedifferences in cell sensitivity,test protocol,