DISTRIBUTION AND CHARACTERIZATION OF NON-VOLATILE CHEMICAL MUTAGENS IN SEDIMRNTS OF AN INDUSTRIALLY IMPACTED RIVER

摘要

A coupled bioassay/analytical fractionation approachwas used to isolate genotoxic contaminants from riversediments collected at points upstream,adjacent to,and downstream from centers of major industrial andmunicipal activities.Sediments were milled withsodium sulfate and sequentially extracted with anonpolar to polar solvent series;extracts were