目的：探索改良电休克治疗（ modified electraconvulsive therapy ，MECT）前后抑郁症患者延迟记忆能力变化情况及影响因素。方法对11例抑郁症患者分别在治疗前、治疗后48小时内进行测验，以中文听觉词汇学习测试（ Chinese auditory learning test，CAVLT）分钟延迟回忆分数为终点指标，同时评定治疗前后患者汉密尔顿抑郁量表（ Hamilton depressive scale ，HAMD）分值。结果 MECT治疗后患者延迟回忆分数降低，差异有统计学意义（t＝4．190，P＝0．002）；MECT治疗后患者HAMD分值降低，差异有统计学意义（ t＝15．493，P＜0．001）；延迟回忆能力改变值与治疗前延迟回忆分数相关（ r＝0．801，P＝0．003）。结论 MECT治疗降低抑郁症患者延迟回忆能力，延迟回忆能力损害程度与治疗前延迟回忆能力有关。%Objective To explore the change of delayed memory in patients with depression before and after the modified electrocon -vulsive therapy ( MECT ) .Methods Eleven patients with depression were tested with Chinese auditory learning test before the treatment and within 48 hours after treatment ,while Hamilton Depressive Scale ( HAMD) was also assessed .Results After treatment of MECT ,the delayed recall scores of patients were significantly decreased (t =4.190,P=0.002);HAMD scores were also significantly decreased (t=15.493, P<0.001 );the change of delayed recall scores were significantly associated with the value of pre -treatment delayed recall scores ( r=0.801,P=0.003).Conclusion MECT impairs the ability of delayed recall in depression patients , and the damage degree of delay recall after MECT is correlated to the ability of pre-treatment delayed recall .
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