毛细管基微流体放大系统流体流量分配的研究

摘要

In this paper, a capillary-based microfluidic control amplifying device was designed.The effect of capillary size, capillary length, fluid flow rate and fluid viscosity on the distribution of microfluidic flow was studied in detail.The results show that with the decrease of capillary inner diameter, the increase of capillary length, fluid flow rate and fluid viscosity, the fluid flow distribution uniformity is better, that is, the variation coefficient (CV) of fluid flow becomes smaller.The empirical formula describing the relationship between CV and its influence parameters is obtained.%微流体在平行通道中的均匀分配是实现微流体控制放量制备粒径单分散性功能微球的重要技术.本研究设计了毛细管基微流体控制放大装置,详细研究了毛细管尺寸、毛细管长度、流体流量以及流体粘度对微流体流量均分的影响.研究结果表明,随着毛细管内径的减小、毛细管长度的增加、流体流量的增大、流体粘度的增加,流体流量分配均匀性更好,即流体流量变异系数(CV)变小.研究获得了描述CV与其影响参数之间关系的经验公式.