抗血小板治疗与胃肠道出血新进展

摘要

Coronary artery disease is one of the most common forms of heart disease. Drug-eluting stents and other percutaneous coronary intervention technologies are maturing and therefore reducing the instances of cardiac events. However, antiplatelet therapy may increase the risk of hemorrhage even as it decreases the incidents of thrombus. It can specifically result in gastrointestinal bleeding. When using anti-platelet therapy it is important to assess the risks and benefits of using antiplatelet therapy and the potential for gastrointestinal bleeding.%冠心病是一种最常见的心脏病,斑块的不稳定、破裂以及血栓形成是贯穿于冠心病发病过程的主要矛盾,随着药物洗脱支架、经皮冠状动脉介入技术日趋成熟,置入药物洗脱支架后联合应用抗血小板聚集药物可明显减少心脏事件的发生.经抗血小板治疗在减少血栓事件的同时也给患者带来了出血的风险,一旦胃肠道出血则对抗血小板治疗形成了十分严峻的挑战,在临床中充分权衡二者的利弊,合理应用.