Patients with acute coronary syndromes( ACS ) have high morbidity and mortality. The rupture of vulnerable plaque in the coronary artery is the initiating factor in ACS. Existing imaging methods of examination include invasive and non-invasive techniques . The first technique focuses on imaging the microanatomy of the plaque to identify the plaque components, and includes high frequency intravascu-lar ultrasound ( IVUS ), virtual histology-IVUS, intravascular optical coherence tomography and intravascular magnetic resonance imaging ( MRI ). The second set of techniques is directed at measuring metabolic activity of the plaque to predict the risk of plaque disruption, and includes intravascular thermography and elastography. The third technique relies on measuring plaque chemical composition and detailed characterization by employing near infrared reflectance or Raman spectroscopy. This article reviews the new progress of the detection of the vulnerable plaques in imaging techniques.%急性冠状动脉综合征是严重威胁人类健康的一种临床综合征.易损斑块的破裂是急性冠状动脉综合征发生的始动环节.当前可应用的诊断技术分为侵入性和非侵入性技术.一方面是通过对斑块组织学的研究来识别斑块内成分,这方面技术包括:血管内超声、血管内超声虚拟组织学、血管内光学断层扫描、血管内磁共振.另一方面是通过测定斑块的代谢活跃程度来预测斑块破裂的危险,包括血管内温度测量法和弹力图.再次是通过测定斑块化学成分及对斑块的特征性描述,包括近红外光谱和拉曼光谱.现就易损斑块在影像学方面检测方法的最新进展予以综述.
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