冠状动脉临界病变是指冠状动脉造影直径法测得狭窄程度为50%~70%的病变.虽然冠状动脉造影作为诊断冠心病的金标准已被大家公认,但是冠状动脉造影只是对狭窄血管进行解剖学评价,不能对病变血管及其支配心肌进行病理生理及功能性评价,对于冠状动脉临界病变采取何种治疗方案也没有可靠的依据.冠状动脉临界病变在临床中十分常见,且部分病变是导致急性冠状动脉综合征的罪犯血管,因此评价临界病变情况与制定治疗决策十分重要.负荷门控核素心肌灌注显像可以同时评价心肌血流灌注情况和心功能,为临界病变患者的治疗提供依据.现就门控核素心肌灌注显像负荷在评价冠状动脉临界病变中的临床价值做一综述.%Intermediate coronary lesion/ stenosis refers to the stenosis degree of 50% to 70% of the coronary lesions measured by cor-onary angiography. Although coronary angiography as the gold standard for the diagnosis of coronary heart disease,has been recognized,but the result is anatomical evaluation of stenosis,not functional,pathological and physiological. The treatment options for intermediate coronary lesion has no reliable basis. The incidence of intermediate lesions is very common in the clinic,and part of the critical lesions is the culprit of acute coronary syndromes. Therefore,it is very important to evaluate the critical disease and make treatment decisions. Stress gated nuclide myocardial perfusion imaging(G-MPI) can evaluate myocardial perfusion and cardiac function simultaneously,and provide evidences for the treatment of patients with intermediate coronary lesion. This review discusses the clinical value of stress G-MPI in evaluating intermediate cor-onary lesion/ stenosis.
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