坤宝丸与西药治疗更年期综合征临床疗效对比分析

摘要

目的：对比分析坤宝丸与西药治疗更年期综合征临床疗效和激素水平。方法：98例更年期综合征妇女依照随机数字表法分为治疗组与对照组。每组各49例。观察组接受坤宝丸，每日两次，每次50粒，给药一个月。对照组接受雌激素疗法，利维爱2．5mg，每天1次，给药一个月。观察2组患者的临床症状、不良反应和激素水平。结果：对照组总有效率为91．8％。治疗组总有效率89．7％。2组的总有效率无明显差异（χ2＝0．12，P＜0．05）。与对照组比较，治疗组中FSH和LH变化幅度与对照组无明显差异（t＝0．11，P＞0．05），结论：坤宝丸治疗更年期综合征的临床疗效与西药利维爱无明显差异，在改善FSH和LH上，和利维爱无明显差异，不良反应小，临床具有一定的可行性。%Objective:To compare the clinical efficacy of Kunbao pill with western medicine in the treatment of menopaus-al syndrome and hormone levels.Methods:98 cases of women were randomly divided into a treatment group and a con-trol group according to random number table.There were 49 cases in each group.The observation group was received 50 Kunbao pills twice a day for a month.The control group was received estrogen therapy of 2.5mg Livial one time every day for one month.The clinical symptoms, adverse reactions and hormone levels were observed between two groups.Re-sults:The total effective rate was 91.8% in the treatment group.The total efficiency rate was 89.7% in the control group.There was no significant difference between two groups (χ2 =0.12, P <0.05 ) .Compared with the control group, the magnitude of change in FSH and LH in the treatment group and the change in the control group had no signif-icant difference ( t=0 .11 ,P>0 .05 ) .Conclusion:The clinical efficacy of Kunbao pill has no significant difference with the efficacy of western medicine in the treatment of menopausal syndrome.Livial has no significant difference with Kun-bao pill for the improvement of the change of FSH and LH.Kunbao pill has less adverse reaction and shows certain clini-cal feasibility.