过渡金属催化碳氢键三氟甲基化

摘要

近几年来,过渡金属催化的碳氢键活化的三氟甲基化反应取得了重要的进展.该领域的反应主要集中于端炔的sp碳氢键活化三氟甲基化反应、芳烃和杂环的sp2碳氢键活化的三氟甲基化反应以及烯丙基sp3碳氢键活化的三氟甲基化反应.本文简要介绍了该类反应的特点,概述了该领域的最新进展、面临的挑战及以后研究发展的重点和方向.%In recent years,transition metal-catalyzed C—H trifluoromethylation has been well developed,which is mainly focused on the terminal alkyne C（sp）—H,aromatic and heterocyclic C（sp2）—H and allylic C（sp3）—H trifluoromethylation.This paper briefly overviews the latest developments in this field,the characteristics of various types of reaction,as well as the facing challenges and future direction.