颈椎人工椎间盘置换术与颈前路减压融合内固定术手术疗效比较

摘要

目的：比较颈椎人工椎间盘置换术（ cervical disc arthroplasty ，CDA）与颈前路减压融合内固定术（ anterior cervical de-compression and fusion ，ACDF）的手术疗效。方法：回顾分析2012年8月～2015年1月收治的退变性颈椎病50例，随机给予CDA（n＝23），或者ACDF（n＝27）治疗，术后12个月门诊随访。结果：两组术前性别、年龄、手术节段活动度（range of motion， ROM）、VAS（ visual analogue scale ）及JOA（ Japanese orthopaedic association ）无统计学差异，CDA组比ACDF组手术时间短，出血量少，具有明显统计学差异（ P＜0．01），两组住院时间无明显统计学差异。术后12个月，两组手术节段ROM差异具有统计学意义（ P＜0．01），CDA组ROM较术前得以维持，ACDF组降低。两组JOA及VAS无统计学差异。结论：CDA较ACDF能维持手术节段的活动度，CDA有望取代ACDF。%Objective:To compare curative effects of Bryan cervical disc arthroplasty ( CDA) with those of anterior cervical decompression and fusion ( AC-DF).Methods:A total of 50 patients with cervical spondylotic myelopathy treated in our hospital between August 2012 and January 2015 were randomly as-signed to two groups.One group were treated with CDA (n=23) and another with ACDF(n=27).Two groups of patients were postoperatively followed on outpatient basis for 12 months.Results:The two groups were not significantly different regarding the gender,ages,range of cervical motion(ROM) and sco-ring on visual analogue scale(VAS) and Japanese Orthopedic Association(JOA).CDA group had shorter operative time and intraoperative blood loss than ACDF group,the difference was significant( P<0.01) .The length of hospital stay remained similar for the two groups ,yet the two groups were different con-cerning the ROM 12 month after operation(P<0.01).Postoperative ROM was maintained in patients in CDA group,whereas was decreased in ACDF group. There was no statistical difference regarding the JOA and VAS scores between two groups .Conclusion:CDA can lead to better maintenance of ROM than ACDF after operation,and the former may be wider clinical recommendation .