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The transport of suspensions in geological, industrial and biomedical applications.

机译:在地质,工业和生物医学应用中的悬浮液运输。

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摘要

Suspension flows in varied settings and at different concentrations of particles are studied theoretically using various modeling techniques. Particulate suspension flows are dispersion of particles in a continuous medium and their properties are a consequence of the interplay among hydrodynamic, buoyancy, interparticle and Brownian forces. The applicability of continuum modeling techniques to suspension flows at different particle concentration was assessed by studying systems at different time and length scales. The first two studies involve the use of modeling techniques that are valid in systems where the forces between particles are negligible, which is the case in dilute suspension flows. In the first study, the growth and progradation of deltaic geologic bodies from the sedimentation of particles from dilute turbidity currents is modeled using the shallow water equations or vertically averaged equations of motions coupled with a particle conservation equation. The shallow water model provides a basis for extracting grain size and depositional history information from seismic data. Next, the Navier-Stokes equations of motion and the convection-diffusion equation are used to model suspension flow in a biomedical application involving the flow and reaction of drug laden nanovectors in arteries. Results from this study are then used prescribe the best design parameters for optimal nanovector uptake at the desired sites within an artery.;The third study involves the use of macroscopic two phase models to describe concentrated suspension flows where interparticle hydrodynamic forces cannot be neglected. The isotropic form of both the diffusion-flux and the suspension balance models are solved for a buoyant bidisperse pressure-driven flow system. The model predictions are found to compare fairly well with experimental results obtained previously in our laboratory.;Finally, the power of discrete type models in connecting macroscopic observations to structural details is demonstrated by studying a system of aggregating colloidal particles via Brownian dynamics. The results from the simulations match experimental shear rheology and also provide a structural explanation for the observed macroscopic behavior of aging.
机译:理论上,使用各种建模技术研究了在不同设置和不同浓度的颗粒下的悬浮液流动。颗粒悬浮液是颗粒在连续介质中的分散,其性质是流体动力,浮力,颗粒间和布朗力之间相互作用的结果。通过研究不同时间和长度尺度的系统,评估了连续体建模技术对不同颗粒浓度的悬浮液的适用性。前两项研究涉及使用建模技术,该技术在颗粒之间的力可以忽略不计的系统中有效,在稀悬浮液流中就是这种情况。在第一项研究中,使用浅水方程或垂直平均运动方程式与颗粒守恒方程相结合,模拟了由稀浊流中的颗粒沉降引起的三角洲地质体的生长和发育。浅水模型为从地震数据中提取粒度和沉积历史信息提供了基础。接下来,运动的Navier-Stokes方程和对流扩散方程用于对生物医学应用中的悬浮液流进行建模,其中涉及载有药物的纳米载体在动脉中的流动和反应。然后使用这项研究的结果为在动脉内所需部位的最佳纳米载体摄取规定最佳设计参数。对于浮力双分散压力驱动的流动系统,求解了扩散通量模型和悬浮液平衡模型的各向同性形式。发现模型预测与我们实验室先前获得的实验结果相当吻合。最后,通过研究通过布朗动力学聚集胶体颗粒的系统,证明了离散类型模型将宏观观察与结构细节联系起来的力量。模拟的结果与实验剪切流变学相匹配,也为观察到的宏观老化行为提供了结构解释。

著录项

  • 作者单位

    The University of Texas at Austin.;

  • 授予单位 The University of Texas at Austin.;
  • 学科 Engineering Chemical.
  • 学位 Ph.D.
  • 年度 2008
  • 页码 155 p.
  • 总页数 155
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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