封面
声明
中文摘要
英文摘要
目录
List of Symbols and Abbreviations
Chapter 1 Introduction
1.1 Overview of flavonoids
1.2 Prenylated flavonoids
1.3 Synthesis of flavonoids
1.4 Claisen rearrangement
1.5 Baker-Venkatarama reaction
1.6 DMDO in organic synthesis
1.7 Mannich reaction
1.8 Hela cell line
1.9 Assay for antiproliferative activity
Chapter 2 Total Synthesis of Icaritin via Microwave Assistance Claisen Rearrangement
2.1 Introduction
2.2 Experimental
2.3 Result and discussion
2.4 Summary
Chapter 3 The First Total Synthesis of Sophoflavescenol, Flavenochromane C and Citrusinol
3.1 Introduction
3.2 Experimental
3.3 Result and discussion
3.4 Summary
Chapter 4 Synthesis of Icaritin andβ-Anhydroicaritin Mannich Base Derivetives and Their Cytotoxic Activities on Hela cells
4.1. Introduction
4.2 Experimental
4.3 Assay for cytotoxic activity
4.4 Results and discussion
4.5 Summary
Chapter 5 Sythesis of Kaempferide Mannich Base Derivatives and Their Antiproliferative Activity on Hela Cells
5.1 Introdution
5.2 Experimental
5.3 General experimental procedure for synthesis of Mannich base derivatives.
5.4 Assay for antiproliferative activity
5.5 Results and discussion
5.6 Summary
Chapter 6 Promoting Hydrolysis of Flavonoid Glycosides by Microwave Irradiation
6.1 Introduction
6.2 Experimental
6.3 Results and discussion
Conclusion
参考文献
Publication
致谢
附录A 合成化合物一览表
附录B 化合物谱图
湖南大学;