Object Modelling of Gene Mutation Data for Variance Analysis

摘要

The Gene Mutation Database represents a rich source of information, however, it lacks the complete data sets which is essential to analyse the trait for indirect association of diseases. To understand the extent of polymorphism present in human gene it requires examining the inheritance patterns. The parameters that need to be considered to analyse the disease are the ethnic origin, frequency of abnormalities, genetic distance between loci (d), mutation rate (μ) and correlation with reported clinical importance. On the basis of these analysis the conceptual schemas for the following mutation data have been developed: trait analysis, gene mutation data, laboratory data and pathological lesions data. We also aim to store the empirical evidences and images in genetic disorder database.