Investigation of interaction between the dynamic polymer surfaces and collagen molecules

摘要

By preparing a polymer loop structure with mobile methylated a-CDs threaded onto PEG backbone, we tried to define the role of dynamicity of the polymer surface to the collagen adsorption and fibrillogenesis. The surface mobility is an important parameter that controls the collagen adsorption and fibrillogenesis. Such property is thought to bring the fast healing process in vivo.