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Organic nano-electro-mechanical-sensor systems for healthcare and environmental applications

机译:用于医疗保健和环境应用的有机纳米电子机械传感器系统

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Organic field effect transistors and polymer microcantilevers are two classes of organic sensors with potential applications in biochemical sensing. The organic field effect transistors (OFETs) with region regular poly3-hexylthiophene(rr-P3HT) and hexafluoro-2-propanol-substituted polysiloxane (SXFA) as an organic layer, have been used for detection of explosive vapors with excellent sensitivity of less than 70 ppt for 1,3,5-trinitro-1,3,5-triazacyclohexane (RDX) and less than 100 ppt for 2,4,6-trinitrotoluene (TNT) [1–3]. Piezo-resistive & piezo-electric polymer composite microcantilevers have been demonstrated as sensitive and cost effective platforms for bio-chemical detection [4–12]. Integration of the OFET and the polymer cantilever platform can bring orthogonality to the sensing where selectivity is a critical requirement. We have recently achieved this by integrating a strain sensitive organic field effect transistor (OFET) on the surface of a polymer nanomechanical cantilever [6]. This sensor named as the “Organic CantiFET” shows the highest deflection and surface stress sensitivity reported till date and opens up opportunities for realizing highly sensitive yet selective low cost polymer sensors for a variety of applications.
机译:有机场效应晶体管和聚合物微悬臂梁是两类有机传感器,在生物化学传感领域具有潜在的应用。具有区域规则聚3-己基噻吩(rr-P3HT)和六氟-2-丙醇取代的聚硅氧烷(SXFA)作为有机层的有机场效应晶体管(OFET)已用于检测爆炸性蒸气,其灵敏度低于1,3,5-三硝基-1,3,5-三氮杂环己烷(RDX)70 ppt,而2,4,6-三硝基甲苯(TNT)小于100 ppt [1-3]。压阻和压电聚合物复合材料微悬臂梁已被证明是灵敏且具有成本效益的生物化学检测平台[4-12]。在选择性是关键要求的情况下,OFET与聚合物悬臂平台的集成可以为传感带来正交性。我们最近通过在聚合物纳米机械悬臂梁的表面集成应变敏感有机场效应晶体管(OFET)[6]实现了这一目标。迄今为止,这种被称为“有机CantiFET”的传感器显示出最高的挠度和表面应力敏感性,为实现适用于各种应用的高灵敏度,选择性低成本的聚合物传感器打开了机遇。

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