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Imaging of biological tissues by means of a time-gated confocal scanning: experimental and numerical results

机译:通过时间门控共聚焦扫描对生物组织成像:实验和数值结果

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Abstract: Numerical and experimental results of a study carried out to investigate the capabilities of the time gating technique to enhance images of biological tissues are reported. In particular we have investigated the confocal scanning configuration. The experimental results were obtained by using a picosecond laser and a streak camera system. The numerical results were obtained by using Monte Carlo simulations. Both elementary and semianalytic Monte Carlo methods were used. The numerical results showed that by using the time gating technique the contrast can be significantly increased when a short gating time is used. The measured time resolved spread functions were in general good agreement with numerical results. However, the experimental results showed that with our experimental setup it is difficult to measure with sufficient accuracy the small energy received during a short gating time when the slab of tissue is larger than 1 cm. !17
机译:摘要:报道了一项研究的数值和实验结果,以研究时间门控技术增强生物组织图像的能力。特别是,我们研究了共聚焦扫描配置。实验结果是通过使用皮秒激光和条纹相机系统获得的。通过使用蒙特卡洛模拟获得数值结果。基本和半解析蒙特卡罗方法都被使用。数值结果表明,通过使用时间选通技术,可以在使用短选通时间时显着提高对比度。测得的时间分辨扩散函数总体上与数值结果吻合良好。然而,实验结果表明,在我们的实验装置中,当组织平板大于1 cm时,很难在短选通时间内以足够的精度测量接收到的小能量。 !17

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