A 64 Channel Programmable Closed-loop Deep Brain Stimulator with 8 Channel Neural Amplifier and Logarithmic ADC

摘要

We describe a 64 channel closed-loop deep brain stimulator IC for use in research and treatment of Parkinson's disease. The system generates programmable stimulation currents and senses and filters neural activity recorded with an 8 channel preamplifier and 200kS/s 8bit log ADC. The entire system implemented in 0.18μm CMOS, occupies 2.67mm{sup}2, and consumes 271μW from a 1.8V supply. In-vivo test data is presented.