The Project Management of Corneal Transplantation in Animal Experiments Based on BP Neural Network

摘要

Corneal diseases are increasing year by year in the world, because of the lack of cornea donation. Thus the management of artificial corneal transplantation becomes much more necessary. As an important stage of medical device research projects, the animal experiments of artificial cornea should be completed before the clinical trials. In this paper, the corneas is prepared from pig eyes. Firstly, the BP neural network is used to train the data of corneal transplantation of 36 New Zealand rabbits, and then to predict the weighted sum of the remaining 4 New Zealand rabbits. Then, the predictive results are compared with the actual data, and the comparison and error analysis reveal the adaptability and accuracy of the predictive results, which can make us carry out the process monitoring of corneal transplantation, and select the optimal artificial cornea. Finally, the project management of corneal transplantation can provide the theoretical support and reference for the management of corneal transplantation, and further lay the experimental foundation for the development of corneal clinical trials.