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In Vitro Degradation of Magnesium Wire in Sternal-Closure-Like Conditions

机译:镁丝在胸骨闭合样条件下的体外降解

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Even with advances in minimally invasive surgery, open heart surgery remains a mainstay of modern medicine. In open heart surgery, the sternum is bisected to allow access to the heart. After surgery, the two halves of the sternum are mechanically fixed with stainless steel wires or in some cases titanium or stainless steel cables and plates. These devices are left behind indefinitely and can in some cases cause patient discomfort or interfere with subsequent operations. An absorbable magnesium wire could allow for sufficient mechanical support while the sternum heals while avoiding the secondary complications of permanent materials. In this study, feasibility of a Mg sternal wire was assessed using a patent-pending LZ21 alloy wire and a simple sternal model mimic. Baseline mechanical and microstructural properties of 0.95 mm wire were established and compared to wire corroded in a modified Hank's fluid while under tension.
机译:即使微创手术取得了进步,心脏直视手术仍然是现代医学的支柱。在心脏直视手术中,胸骨被一分为二以允许进入心脏。手术后,胸骨的两半用不锈钢丝或在某些情况下用钛或不锈钢电缆和板机械固定。这些设备会无限期地留下,在某些情况下会导致患者不适或干扰后续手术。可吸收镁丝可以在胸骨愈合时提供足够的机械支撑,同时避免永久性材料的继发性并发症。在这项研究中,使用正在申请专利的 LZ21 合金线和简单的胸骨模型模拟物评估了 Mg 胸骨线的可行性。建立了 0.95 mm 线材的基线机械和微观结构特性,并与在张力下在改性 Hank 液中腐蚀的线材进行了比较。

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