Synthesis and Studying Induction Heating of Mn1-xZnxFe_2O_4 (x=0- 0.5) Magnetic Nanoparticles for Hyperthermia Treatments

摘要

The current development confirms the need for magnetic nanoparticles in tumors treatment to become more safety in thermal therapy. Self-regulate magnetic nanoparticles of MnZnFe_2O_4 may be proper for thermal treatments. The structure and magnetic properties of the synthesis Mn_(1-x)Zn_xFe_2O_4 with x=0-0.5 by step 0.1were studied. Nanoparticles of MnZnFe_2O_4 were prepared by the co-precipitation method and followed by heat treatment in an autoclave reactor. XRD results showed that it had been difficult to prepared MnZn-ferrite directly by using the coprecipitation method. FESEM images confirmed that the preparation method produced spherical nanoparticles with a slight change in the particle size distribution, as well as the Particle size has shrunk after the heat treatment. The average particle size has estimated to be about 20 nm. FTIR spectra of samples showed two distinct absorption bands, the band at ~ 617(cm-1) and the ~426 (cm-1) to the tetrahedral and octahedral site respectively were assigned. The absorption bands of the tetrahedral site slightly shifted towards high frequency with increasing zinc content. According to a magnetic measurement, the study indicates the size of particles is sufficiently small to behave superparamagnetically, the hysteresis loop curves perfectly matched;;it shows typical soft magnetic materials. The heating ability of water-based colloidal dispersions studied under magnetic field strength 6.5 kA/m and the frequency 190 kHz. The results showed that when increasing Zn~(2+) concentration to 0.3 or more;;the temperature of fluids was not raised. Depending on the increase in the heating curve, the susceptibility, effective relaxation time and Neel relaxation time were determined.