Self-Assembled Monolayers for Anti-Fouling and Highly Selective Electrode Interfaces

摘要

The detection, collection and/or conversion of biological-based molecules has applications to sensing, wearables, and biofuels. Flexible, wearable electronics for real-time detection of, for example, Neuropeptide Y in human sweat, or flagella protein in biofuels, enables deviation from bulky laboratory benchtop analyses such as ELISA. Challenges include required limits of detection, as biological materials can be present in small amounts (nM to pM concentrations) in complex high ionic strength environments, the need for a highly selective sensor interface that avoids nonspecific binding, and a quick response to account for degradation of analytes.