(Invited) Electrochemical Dehydrogenative Cyclization Using a Halogen Mediator for the Synthesis of Thienoacene Derivatives

摘要

The formation of carbon-sulfur bond is one of the fundamental and important transformations in organic synthesis because C-S bonds are abundant and important skeleton in the field of pharmaceuticals and material science. For example, the antidepressant vortioxetine, and an antifungal medication sertaconazole are useful medicines. π-Expanded benzo[b]thiophene derivatives, such as benzothieno[3,2-6]benzothiophene (BTBT) and dinaphtho[2,3-b:2',3'-d]thiophene (DNT), have received considerable attention as key building blocks for use in organic field effect transistors.