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Skeletal Muscle Construct in Vascularized Cylindrical Chamber

机译:血管化圆柱形室中的骨骼肌构建

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A construct containing functional skeletal muscle tissue was formed in vivo within an axially vascularized chamber seeded with myoblasts suspended in a gel. After a three week period of incubation within a rat, the construct was harvested and evaluated for force generation capability. Constructs that were seeded with myoblasts generated a positive component of force (to shorten the construct), having contractile properties similar to those of skeletal muscles.
机译:含有功能性骨骼肌组织的构建体在轴向血管化的室内的用悬浮在凝胶中悬浮的轴向血管化室内形成。 在大鼠内孵育三周后,收获构建体并评估力产生能力。 用肌细胞播种的构建体产生了阳性部件(以缩短构建体),具有与骨骼肌类似的收缩性质。

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