The Influence of Transcranial Electrostimulation on Blood Pressure in Dogs with Modeled Hypertension

摘要

The present article describes the results of the transcranial electrostimulation (TES) for the correction of blood pressure (BP) in dogs. During the experiment, systolic blood pressure (BPs), diastolic blood pressure (BPd), pulse pressure (PP), and mean blood pressure (MBP) were registered. It was established that TES mode that switched on the electrodes feeding that were fixed on the animal head at constant current (gradually increasing from 0 to 6 mA) with further switching to 75 Hz 4.0 mA square-wave pulse (impulse duration - 3.5 ms) for 30 minutes exerted corrective effect on blood pressure in dogs with pharmacologically modeled hypertension. The results of the performed tests showed that after the injection of mesatone, midodrine, and norepinephrine, the studied BP parameters elevated in all the dogs. In animals from the test groups that were injected drugs in combination with TES, the BP parameters increased insignificantly (p>0.05). In the dogs from the control groups, the increase in the BP parameters was significant in the majority of cases (p<0.05). The most significant differences between the studied parameters were observed in groups that received mesatone in combination with TES. It was revealed that after the injection of the drug and performance of TES in animals from the test group, BPs ranged within 139.7±8.8 -146.6±8.7; BPd ranged within 78.8±6.8 - 80.0±5.0; PP -60.0±5.8 - 67.8±5.7; MBP - 99.7±7.8 - 101.4±7.0 mmHg. In animals from the control group that did not receive TES, the parameter values were higher and ranged within 151.0±8.8 -170.5±8.9; 80.3±6.4 - 98.9±7.3; 70.0±7.0 - 71.6±6.9; 103.9±8.0 -122.8±8.1 mmHg, respectively. It is recommended to use TES in practical veterinary to the correction of blood pressure in dogs.