Poly(Vinyl Alcohol)/Chitosan Nanofibrous Membrane Containing Anredera Cordifolia (Ten.) Steenis

摘要

A novel nanofibrous membrane that has potential application as antimicrobial wound dressing has been developed. The membrane consisted of PVA and chitosan as a matrix and extract of Binahong leaves as an active antibacterial material for wound dressing. In this study, ex situ fabrication of nanofibrous membrane composed of polyvinyl alcohol)/chitosan/extract of binahong leaves were described. The fibers were electrospun from a precursor solution composed of 10 ml of PVA 14 %w/v, 2 ml of chitosan 2 % w/v and 4 ml of extract of binahong leaves 2.5% w/v. Nanofibrous membrane yielded from this method was characterized by Scanning Electron Microscopy (SEM), and X-Ray Diffraction (XRD). SEM result showed that morphology and diameter of nanofibers were affected by applied voltage and flowrate. Through X-RD it was found that the addition of binahong leaves extract decreased the crystallinity of the electrospun PVA/chitosan nanofibrous membrane.