Development of Methods for Molecular Construction throughDirect C-H Bond Transformation

摘要

We have been working on the development of effective methods for molecularconstruction applicable to producing various organic fine chemicals including medicinesand organic functional materials which are significantly supporting affluent human society.In particular,we have extensively studied on aromatic cross-coupling reactions through C-Hbond cleavage leading to new C-C and C-heteroatom bonds.The research strategies involvedirecting functional group control and utilization of unique properties of reaction substratesand catalysts,which enable efficient regioselective coupling reactions.The following ourrecent research achievements are presented in this lecture.