Characteristics and Micromorphology of New Collagen Scaffolds Derived from Supercritical Fluid of Carbon Dioxide with Alcohol Cosolvents

摘要

Supercritical Carbon dioxide fluid provides the advantage of high diffusion capacity during natural product extraction, maintains thermal instability and maintains the biological activity of the extract. The cell extraction process used to remove cellular components from pig skin must remove fat and other impurities almost through supercritical fluid (SCF), otherwise the fat tissue will rot immediately. The choice of cosolvents may also affect the results during supercritical processes. The preparations of new collagen scaffolds by using supercritical fluid of carbon dioxide with alcohol cosolvents. Different characteristics and micromorphology of the new collagen scaffolds could be observed by using treatments of different cosolvent substitutions and cosolvent concentrations in supercritical carbon dioxide fluids system.