Antibacterial Activities of Extract Curly Chili (Capsicumannum. L) on Fusobacterium Nucleatum: An in Vitro Study

摘要

The progress of most caries process caused the root canal infection. Bacteria that dominated in root canal infection were Fusobacterium nucleatum bacteria that were 48%. This infection needed endodontic treatment. One of the influencing factors was microorganism. It can be eradicated by root canal irrigation. The common substance used for root canal irrigation was Chlorhexidine 2%. However, there are many researches done nowadays to find the alternative substances that are originated from nature. Curly chili is one of the alternatives that can be chosen as root canal irrigation material because it contains the substance useful as antibacterial that is capsaicin. The purpose of this research was to know the effect of Curly chili extract (Capsicum annuum, L) to the development of Fusobacterium nucleatum bacteria. It was the laboratory experimental research. Statistical analysis used Kruskall-Wallis test. The result of the research showed that the highest barrier zone diameter average at 100% concentration was 23.50 mm and control (+) 24.50 mm with p=0.000 (<0,05). Based on the research, it can be concluded that there was antibacterial activity of Curly chili (Capsicum annuum, L) in concentration of 20%, 40%, 60%, 80%, 100% and control (+) to pursue the growth of Fusobacterium nucleatum bacteria. Higher concentration of Curly chili extract (Capsicum annuum, L) was stronger barrier for the growth of Fusobacterium nucleatum bacteria.