Development of ratiometric carbohydrate sensor based on boron dipyrromethene (BODIPY) scaffold.

摘要

In this study, we have designed a ratiometric fluorescence saccharide indicator based on the fluorophore boron dipyrromethene (BODIPY). The detection of biologically important sugars are vital as they are involved in the metabolic pathways of living organisms. Boronic acids serves as the useful chelator groups for sugar recognition, where they can bind with compounds containing diols with high affinity through reversible ester formation.