Effect Of Vitamin E on Human Periodontal Ligament Fibroblasts

摘要

INTRODUCTION The periodontal ligament fibroblasts plays an essential role in the organization and maintenance of the connective tissue during development and in response to injuries and diseases. They are also responsible of the migration and differentiation of the variety of cells that takes part in the osteogenesis in response to external forces (1, 2). Age related changes include decreased fibroblasts density and cellular activity which slows orthodontic tooth movement due to prolonged response of the connective tissue to external forces which poses a potential risk in orthodontic treatment (3, 4).