At the ACVIM forum in 2006 a panel discussion was presented on lumbosacral (LS) disease. While there has been clinical scientific information published in the last 10 years, the convening of this panel suggests that a number of clinical questions remain unanswered.What is the spectrum of pathophysiologic abnormalities that occur under the clinical label of 'lumbosacral disease'?How are each of the pathophysiologic components definitively diagnosed?What is the role of the various imaging modalities in supporting/confirming the diagnosis?What is the contribution of foraminal size alterations to the clinical signs and progression?What is the contribution of instability to the clinical signs and progression?What is the contribution of vascular alterations to the clinical signs and progression?What is the most effective treatment?What are the advantages and disadvantages of the various surgical treatments?What is the natural course of the disease process without treatment?
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