Effects of External Application of Ginkgo Semen Paste on Tinea Corporis Model of Rat

摘要

Objective: To investigate the effects of external application of Ginkgo Semen (GS) paste on tinea corporis model of rat. Methods: Tinea corporis rats model were established by vaccination trichophyton mentagrophytes in skin wound. Observe the effects of the high, low dose of GS alcohol paste group and the high, low of GS water paste on symptoms integral before and after treatment, the skin lesions inverse culture and the local tissue morphology in tinea corporis rats model. Results: Tinea ulcer model rats successfully. Compared with the model group, the high, low dose of GS alcohol paste group and the high, low GS water paste could significantly or remarkably reduce the symptoms integral, remarkably increase the skin inverse culture turn rate and improve the pathological changes. Conclusion: The external application of GS paste has remarkable curative effect on tinea corporis rats model.