A Miniature Bio-Photonics Companion Diagnostics Platform for Reliable Cancer Diagnosis and Treatment Monitoring (BioCDx)

摘要

Current diagnostic options for cancer treatment monitoring rely on imaging techniques and cannot guarantee proper assessment of therapeutic response. BIOCDx aims to develop a disruptive PoC device for cancer early diagnosis and treatment monitoring as a companion diagnostics tool. One of the scientific breakthroughs of this project is the development of a "cancer stem cells" detection platform by virtue of expression of the cancer stem cell-specific transcription factor TWIST 1, which controls the expression of circulating biomarkers. Cancer stem cells represent the most aggressive/tumorigenic cell compartment within tumors.