Isolation, Characterization and Engineering of Single Domain Antibodies for the Development of Bioactive Paper Against Listeria monocytogenes

摘要

The incident rate of Listeriosis in Canada has doubled from 2.3 (2000) to 4.5 cases (2007) per million (1). The most recent and severe Listeriosis outbreak in Canada was in 2008 with 22 reported deaths and 57 confirmed cases due to the consumption of cold cuts contaminated with Listeria monocytogenes(2). Even though food manufacturers and processors take stringent measures to control the pathogen in manufacturing units, food continues to be recalled from stores, as every stage of the food chain, from plough to plate, is prone to contamination by L. monocytogenes(3).