Scale-up of membrane affinity adsorbers based on tested physical model

摘要

Membrane chromatography represents one of the emerging technologies for downstream processing in the biotechnology industry. This process is currently used in polishing steps for antibody manufacturing, while its application it is still uncommon for the capturing step. To promote its application in large scale processes, it is imperative to develop a reliable simulation tool able to describe the process performance at all scales in a predictive way.