(S7.11-S0046) Corrosion behavior of hydrophilic polymer coated biodegradable magnesium alloy in culture medium

摘要

Magnesium and its alloys are a promising alternative to biodegradable polymers like poly(L-lactic acid) due to their degradation ability combined with appropriate mechanical propertiesand good biocompatibility. The main limitation on the application of Mg alloys to medicalimplants is their corrosion behavior. Corrosion is too rapid and not homogeneous, due to a strongtendency for localized corrosion exhibited by Mg alloys. Various coatings are suggested to increasethe corrosion resistance. Vascular stent surface is expected to prevent the protein adhesion whichtriggers cell adhesion. Polyethylene glycol (PEG) prevents the protein adhesion and is used as ananchor of biomolecules to the implant surface. However, PEG has not been examined as corrosionprotection coatings of Mg alloys due to the hydrophilic property. The purpose of the present studywas to elucidate the corrosion protection effect of PEG coatings on Mg alloy.