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Palm oil nanoemulsion hydrogels: Formulation and stability studies

机译:棕榈油纳米乳液水凝胶:配方和稳定性研究

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In this present study, the palm oil nanoemulsion hydrogels were formulated and stability of palm oil nanoemulsion hydrogels were investigated. The nanoemulsion hydrogel formulations that passed through droplet size test were characterized for viscoelastic behaviour. The best formulation was the one with composition of 10% palm oil (5:1 PO:L1695), 4.67% glycerine, 0.5% Carbopol 934 and 82.83% de-ionised water. The composition is considered the best due to small droplet size (127.5±1.60nm) and, exhibited a stable range of zeta potential (−51.6±4.38mV) after being kept for three months at 4°C. Furthermore, the selected formulation gave a pleasant feeling upon application onto skin with a good structure stability and spreadability on skin based on the oscillation frequency sweep test.
机译:在本研究中,调节了棕榈油纳米乳胶水凝胶,研究了棕榈油纳米乳胶水凝胶的稳定性。 通过液滴尺寸试验的纳米乳液水凝胶制剂用于粘弹性行为。 最佳配方是具有10%棕榈油(5:1 PO:L1695)的组成的配方,4.67%甘油,0.5%Carbopol 934和82.83%的去离子水。 由于小液滴尺寸(127.5&#00b1; 1.60nm),该组合物被认为是最佳的,并且在4个月内保持三个月后,展示了稳定的ζ电位范围(− 51.6± 4.38mv) #x00b0; c。 此外,所选择的制剂在施加到皮肤上具有良好的结构稳定性和皮肤铺展性的舒适感,基于振荡频率扫描测试。

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