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Self-Assembled Lipid Tubules: Synthesis, Characterization, and Ordered Arrays

机译:自组装脂小管:合成,表征和有序阵列

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The rolling of lipid bilayer sheets into hollow cylindrical tubules have emerged as a group of interesting supramolecular nanostructures. Here, we image the self-assembled tubules of 1,2-bis(tricosa-10,12-diynoyl)-sn-glycero-3-phosphochloline (DC{sub}(8,9)PC) with atomic force microscopy. Nanoscale ripple structures with a periodicity of ~200nm in the cylindrical lipid tubules are observed. We develop two simple methods based on microfluidic networks (μFN) and surface patterning to produce two dimensional ordered arrays of parallel aligned lipid tubules on substrates.
机译:将脂质双层片材卷成中空圆柱形小管,作为一组有趣的超分子纳米结构。这里,我们用原子力显微镜图像将1,2-BIS(Tricosa-10,12-diyyynoyl)-sn-甘油-3-磷啉(Dc {sub}(8,9)pc)的自组装小管图像。观察到圆柱形脂质小管中具有〜200nm的周期性的纳米级纹波结构。我们基于微流体网络(μFN)和表面图案化的两种简单方法,以在基板上产生二维有序的平行对准脂质小管阵列。

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