Optical properties of porcine oral mucosa at application of iodine preparation based on glycerol

摘要

The use of diffuse reflection spectroscopy made it possible to determine the optical properties of the mucous membrane of the oral cavity of a pig. The binary diffusion coefficient of iodine in Lugol's composition (aqueous solution of iodine (0.01 w/w), potassium iodide (0.02 w/w) and glycerol (0.94 w/w)) was determined for the first time ex vivo in the lining of the alveolar gingiva pigs: (8.86±0.75)·10~(-7) cm~2/s. For the first time, the binary diffusion coefficient of glycerol was determined in the composition of Lugol (an aqueous solution of iodine (0.01 w/w), potassium iodide (0.02 w/w), and glycerol (0.94 w/w)) ex vivo in the lining of the alveolar gingiva pigs: (6.44±0.62)·10~(-7) cm~2/s. It was revealed that after complete staining of the gingiva with a dye, radiation does not pass into the biological tissue from 200-600 nm, which includes the areas of iodine absorption peaks, and starting from 650-800 nm, the effect of optical clearing is observed with an efficiency of up to 120%.