Blood Purification for Paediatric Patients

摘要

Background: Recenttechnical and experimental advances in extracorporeal blood purification therapy (eBPT) can be applied in paediatric patients, including neonates. However, there are several specific issues in performing eBPT in paediatric patients in regard to the safety and effectiveness of treatments. The aim of this review is to explore the technical aspects of acute paediatric eBPT, especially regarding renal replacement therapy and the present situation in Japan. Summary: In children requiring eBPT, especially small children and neonates, it is difficult to secure sufficient blood flow to obtain optimal treatment effects for various diseases and critical illnesses. In such conditions, it should be considered which modalities of eBPT and anticoagulants are used and how optimal blood flow and replacement fluid/dialysate flow rate should be chosen for the safety and effectiveness of treatments.