Adsorption Mechanisms of Gemcitabine Molecules on the Surface of Fe_3O_4 Nanoparticles with Biocompatible Coatings

摘要

1 Introduction Gemcitabine is the synthetic drug, in which chemical structure is an analogue of the pyrimidine bases of nucleic acids. It is primarily used for anticancer therapy of hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (VPHC), which are the most common malignant neoplasms of the liver [1, 2].