Fabrication of Poly Caprolactone (PCL) Based Microspheres for Drug Delivery and Tissue Engineering Application

摘要

This paper reports the fabrication of poly(caprolactone) (PCL) based biodegradable microspheres using freeze-drying technique for drug delivery and tissue engineering application. Microspheres play an important role in tissue engineering and drug delivery applications. The properties can determine the success or failure of the development of the materials. Biodegradable and biocompatible synthetic polymer, PCL was used to fabricate biodegradable microspheres in this study. Through a double emulsion and freeze-drying technique, the microspheres were produced. Different concentrations of polymers were used to fabricate the microspheres. The microspheres were characterized using different techniques.