Research of two-component system genes in phytopathogen bacteria

摘要

In bacteria, two-component systems (TCS) are widely-used signal transduction devices which are adapted to environmental stress and essential for survival. Many phytopathogens encounter different microenvironments during their infectious cycle and their ability to efficiently adapt to different niches inside and outside of their host organisms is frequently mediated by TCS, which can, therefore, be considered as an essential prerequisite for their pathogenicity. Although significant progress has been made in the elucidation of basic principles of the signal transduction process itself, in many pathogens, the contribution of TCS to bacterial virulence is insufficiently recognized.