首页> 外文会议>International Federation for Medical and Biological Engineering European Conference >Mapping of the Magnetic Field in a Prototype Developed for Magnetic Stimulation of Bone Fractures in Animal Models
【24h】

Mapping of the Magnetic Field in a Prototype Developed for Magnetic Stimulation of Bone Fractures in Animal Models

机译:用于磁刺痛动物模型骨骨折的原型中磁场的映射

获取原文

摘要

Biological tissue healing has been developed in many research protocols, once the use of biomaterials and technologic devices during postoperative period may enhance functional and aesthetic rehabilitation. The objective of this paper was to map the magnetic field in a prototype developed for bone healing stimulation in animal models. The prototype was developed with two parallel magnets positioned in attraction to each other. The magnets were fixed and allowed to move in all directions through 3 screws. The animal model chosen was Wistar rat and the fracture model was an incomplete femur osteotomy gap. The animals were divided in 4 groups of magnetic stimulation. The experimental times were 7, 14, 21 and 28 postoperative days. The field's intensity perpendicular to the osteotomy gap was ranged from -101 to -216 mT in the center of the magnetic prototype. During the postoperative stimulation, the osteotomy gap was positioned perpendicular to the center of the field. The project was submitted to the Ethical Research Committee of Positivo University and was approved under the protocol 006/2009. To the result analysis, it was measured the field intensity with a gaussimeter in 60 positions. The data were showed in graphics. Further histological and mechanical analysis will be performed on the bone specimens. As unpublished results it is expected to be possible to develop an experimental protocol to be used in future animal researches and bone fracture's models.
机译:一旦在术后期间使用生物材料和技术装置,就已经在许多研究方案中开发了生物组织愈合可能会增强功能性和审美康复。本文的目的是在动物模型中为骨愈合刺激开发的原型中映射磁场。原型是用两个平行的磁铁开发,其彼此定位在吸引力中。磁体被固定并允许在所有方向上移动3螺钉。选择的动物模型是Wistar RAT,骨折模型是一种不完全的股骨骨质切除术。将动物分为4组磁刺激。实验时间为术后7,14,21和28天。磁性原型中心的恒定垂直于截端术间隙的强度范围为-101至-216mt。在术后刺激期间,骨质图间隙垂直于该领域的中心定位。该项目已提交给实体大学的道德研究委员会,并根据“议定书”006/2009批准。为了结果分析,测量了60个位置的高斯计的场强。数据显示在图形中。将在骨标本上进行进一步的组织学和机械分析。作为未发表的结果,预计可以开发一种在未来的动物研究和骨骨折模型中使用的实验方案。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号