Synthesis, Spectral Characterization and 3D Molecular Modeling of Some Novel Nickel(II) Complexes Derived from 4-Aminoantipyrine

摘要

Some novel Ni(II) complexes with the ligand (z)-4-((2-hydroxy-4-methoxyphenyl)diazenyl)-1,5-dimethyl-2- phenyl-1H-pyrazole-3(2H)-one, 3-methoxy phenol azoantipyrine, L having the formulae [Ni(L)_2X_2] and [Ni(L)_2(Y)Cl] where X = Cl~- / NO_3; Y = NCS~- were synthesized and characterized by elemental analysis, molar conductance measurements, magnetic susceptibility measurements, spectral (IR, UV-Visible, EPR, FAB-mass) studies, thermo gravimetric analysis and by TEM image. Energy minimized configuration of the complex [Ni(L)_2Cl_2] was made with CHEM Bio 3D Ultra 11.0 and the respective parameters were computed. The ligand and the complex [Ni(L)_2(Y)Cl] were screened for their antibacterial activities. An octahedral structure is tentatively proposed for the complexes.